李沁桐

1. 學歷：博士 2. Email: liqintong@scu.edu.cn; qintong.li@gmail.com 3. 研究方向：干細胞生物學 4. 教育經歷：美國愛荷華大學博士，美國哈佛大學、美國加州大學舊金山分校博士后 5. 近五年科研項目： ? ?-國家自然科學基金/美國國立衛(wèi)生院合作項目，已結題、主持，2013/01-2013/12 ? ? - 國家自然科學基金面上項目，在研、主持，2012/01-2015/12 ? ?-國家自然科學基金面上項目，已結題、主持，2010/01-2012/12 6. 代表性論文： （1）. ?A distinct ex-x-pression pattern of cyclin K inmammalian testes suggests a functional role in spermatogenesis. Xiang X, Deng L, ZhangJ, Zhang X, Lei T, Luan G, Yang C, Xiao ZX, Li Q, Li Q. PLOS ONE, 2014 Jul 8;9(7):e101539 （2）. ?IGF-1 regulates the SIRT1-p53 pathwayin cellular senescence. ? Tran D,Bergholz J, Zhang H, He H, Wang Y,Zhang Y, LiQ, Kirkland JL, Xiao ZX.Aging Cell, 2014 Aug;13(4):669-78. （3）. ?Primordial dwarfism gene links Lin28 to safeguardembryonic stem cell from premature differentiation.Dai Q,Luan G, Deng L,Lei T,Kang H,Song X, Zhang Y, Xiao ZX, Li Q.Cell Reports, 2014 May 8;7(3):735-46. （4）.PKCphosphorylatesHEXIM1 and regulates PTEFb activity. Fujinaga K, BarboricM, Li Q, Luo Z, Price DH,Peterlin BM. Nucleic Acids Research, 2012 Oct;40(18):9160-70 （5）. Cyclin K-containingkinase complexes maintain self-renewal in murine embryonic stem cells. Dai Q, Lei T, Zhao C,Zhong J, Tang YZ, Chen B, Yang J, Li C, Song X, Li L, Li Q.Journal of Biological Chemistry, 2012 Jul 20;287(30):25344-52 （6）. ?Genetic analysis of P-TEFb function viaheterologousnucleic acid tethering systems. Li Q, Peterlin BM. Methods, 2009 Aug;48(4):375-80 （7）. ?Cyclin T2 is essential for mouseembryogenesis. Kohoutek J, Li Q, Blazek D, Luo Z, Jiang H,Peterlin BM. Molecular and Cellular Biology, 2009Jun;29(12):3280-5，共同第一作者 （8）. ?Nucleophosmin interacts with HEXIM1 andregulates RNA polymerase II transcription. Gurumurthy M, Tan CH, Ng R, ZeigerL, Lau J, Lee J, Dey A, Philp R, Li Q,Lim TM, Price DH, Lane DP, Chao SH. Journal of Molecular Biology, 2008 Apr 25;378(2):302-17 （9）.MicroRNA regulationof stem cell fate.Li Q, Gregory RI. Cell Stem Cell, 2008 Mar 6;2(3):195-6 （10）. ?Systematic analysis of the

干細胞生物學